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1.
J. Health Biol. Sci. (Online) ; 7(1): 26-31, jan.-mar. 2019. tab, graf
Article in Portuguese | LILACS | ID: biblio-969718

ABSTRACT

Introdução: Estudos comparam taxa de óbitos de Unidade de Terapia Intensiva (UTI) no Brasil que se encontra acima da internacional, não se sabendo se isso é devido ao sistema público brasileiro ou a falhas de registro. Objetivo: Traçar uma relação entre mortalidade prevista e características dos pacientes internados na UTI de hospital terciário de grande porte do município de Fortaleza, Ceará. Métodos: Trata-se de um estudo retrospectivo, analítico e transversal sobre pacientes internados na UTI do Hospital Geral de Fortaleza de janeiro a novembro de 2016. Resultados: No período da pesquisa, foram estudados 137 pacientes; desse total vieram a óbito 31 pacientes (24,48%). De acordo com a prioridade estabelecida pela Society Critical Care Medicine para Unidade de Terapia Intensiva, tivemos 53,3% na prioridade I, 10,0% na prioridade II, 30,0% na prioridade III, 3,3% na prioridade IVA e 3,3% na prioridade IVB, resultados estatisticamente significantes (p=0,012). Constatou-se neste trabalho que 80,6% dos óbitos haviam desenvolvido sepse durante o internamento na UTI (p<0,001). Aplicando-se os escores de mortalidade APACHE-II e SOFA, observa-se que o APACHE-II com escore médio de 22 pontos e com mortalidade prevista média de 55,7 (p<0,001), enquanto, o SOFA teve média no primeiro dia de 7 pontos (p<0,001), no quinto dia de 5 pontos (p=0,004) e no décimo dia de 5 pontos (p=0,004). Conclusão: Observou-se a importância da análise epidemiológica em relação aos óbitos ocorridos em Unidades de Terapia Intensiva, visando demonstrar a necessidade de se conhecer melhor a aplicabilidade dos escores SOFA e APACHE II e as medidas que devem ser adotadas.(AU)


Introduction: Studies comparing rate of deaths of an Intensive Care Unit (ICU) in Brazil that is above international standards, not knowing whether this is due to the Brazilian public system or failures of record. Objective: To establish a relationship between predicted mortality and characteristics of patients admitted to the Intensive Care Unit of a hospital in city of Fortaleza, Ceará. Methods: This was a retrospective study, analytical and cross patients admitted to the Intensive Care Unit of a General Hospital of Fortaleza during the period from January to November 2016. Results: At the time of the study, were studied 137 patients, this total of patients died 31 patients (24.48%). In accordance with the priority set by the SCCM to ICU, we had 53.3% in the priority I, 10.0% in the priority II, 30.0% in the priority III, 3.3% VAT priority and 3.3% in the priority IVB, the results were statistically significant (p=0.012). It was found in this study that 80.6% of deaths developed sepsis during hospitalization in the ICU (p<0.001). Applying the mortality scores APACHE-II and SOFA, it is observed that the apache-II with a mean score of 22 points, with a standard deviation of 8 points, and with the predicted mortality average of 55.7 (p<0.001). While, the SOFA was on the first day of 7 points (p<0.001), on the fifth day of 5 points (p=0.004) and on the tenth day of 5 points (p=0.004). Conclusion: There was the importance of epidemiological analysis in relation to deaths occurring in Intensive Care Units, aiming to demonstrate the necessity of knowing more about the applicability of the scores SOFA and APACHE II and the measures that ought to be taken in cases of high mortality risk.(AU)


Subject(s)
Intensive Care Units , Mortality , APACHE , Organ Dysfunction Scores
2.
São Paulo med. j ; 133(1): 43-50, Jan-Fev/2015. tab, graf
Article in English | LILACS | ID: lil-733008

ABSTRACT

CONTEXT AND OBJECTIVE: Glomerular disease registries are increasing all around the world. The aim of this study was to evaluate the clinical characteristics and treatment response among patients with glomerular diseases followed up in a tertiary hospital in Brazil. DESIGN AND SETTING: Analytical cross-sectional study; tertiary-level public hospital. METHODS: This study included patients with glomerular diseases followed up at a tertiary hospital in Fortaleza, northeastern Brazil. Clinical and laboratory data on each patient were registered. The response to specific treatment was evaluated after 3, 6 and 12 months. RESULTS: The study included 168 patients of mean age 37 ± 14 years. The most prevalent glomerular diseases were focal segmental glomerulosclerosis FSGS] (19.6%), minimal change disease MCD] (17.9%), membranous nephropathy MN] (16.7%) and lupus nephritis LN] (11.9%). The main clinical presentations were nephrotic proteinuria (67.3%) and renal insufficiency (17.9%). The mean proteinuria value decreased after the treatment began. Regarding 24-hour proteinuria on admission, there was no significant difference between patients with a good response and those with no response (7,448 ± 5,056 versus 6,448 ± 4,251 mg/24 h, P = 0.29). The glomerular disease with the highest remission rate was MCD (92%). Absence ...


CONTEXTO E OBJETIVO: Registros de glomerulopatias estão aumentando em todo o mundo. O objetivo deste estudo é avaliar as características clínicas e a resposta do tratamento de pacientes com glomerulopatias acompanhados em um hospital terciário no Brasil. TIPO DE ESTUDO E LOCAL: Estudo transversal analítico. Hospital público terciário. MÉTODOS: O estudo incluiu pacientes com glomerulopatias acompanhados em um hospital terciário de Fortaleza, Ceará, Brasil. Foi realizado registro dos dados clínicos e laboratoriais para cada paciente. A resposta ao tratamento específico foi avaliada após 3, 6 e 12 meses. RESULTADOS: Foram incluídos 168 pacientes, com média de idade de 37 ± 14 anos. A glomerulopatia mais prevalente foi a glomerulosclerose segmentar e focal GESF] (19,6%), seguida pela doença de lesão mínima DLM] (17,9%), nefropatia membranosa NM] (16,7%) e nefrite lúpica NL] (11,9%). As principais manifestações clínicas foram proteinúria nefrótica (67,3%) e insuficiência renal (17,9%). A média dos valores de proteinúria diminuiu após o início do tratamento. Com relação à proteinúria de 24 horas na admissão, não houve diferença significativa entre os pacientes com boa resposta ao tratamento ...


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Adrenal Cortex Hormones/therapeutic use , Glomerulonephritis/drug therapy , Glomerulosclerosis, Focal Segmental/drug therapy , Brazil/epidemiology , Cross-Sectional Studies , Cyclosporine/therapeutic use , Follow-Up Studies , Glomerulonephritis/epidemiology , Glomerulonephritis/pathology , Glomerulosclerosis, Focal Segmental/epidemiology , Glomerulosclerosis, Focal Segmental/pathology , Prevalence , Prognosis , Proteinuria/blood , Remission, Spontaneous , Renal Insufficiency/complications , Tertiary Care Centers/statistics & numerical data , Time Factors , Treatment Outcome
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